Bac3Gel

Modelling human mucus

TECHNOLOGY

Bac3Gel technology aims to model a range of different human mucus in physiological and pathological conditions.

Due to the distinctive features of Bac3Gel, it is also possible to recreate human microbiota in vitro to be used by Pharma, Cosmetic and Food Industries, Contract Research Organisations (CRO) and Research laboratories.

Bac3Gel is an upcoming startup from Politecnico di Milano.

 

Mucus Models

Models of physiologic or pathologic mucus of different body districts: lung, intestinal, stomach or vaginal. 

Gradient Structure

Bac3Gel can be made with a gradient of oxygen, nutrients and bacterial motility. 

Compatibility

Compatible with multiwell plates, bioreactors, Transwell(R), PAMPA systems and cell monolayers. 

Microbiota in vitro

            Simultaneously hosts            different and competitive microorganisms.

Fully tuneable

The chemistry, gradient, viscoelastic properties, structure and thickness of Bac3Gel are fully tuneable. 

Mucus barrier

Reproduces the interactive and steric barriers of human mucus, for appropriate drug screening. 

POTENTIAL APPLICATIONS

Compound permeability through the human mucus barrier

Universal 3D substrate for bacterial culture

Antimicrobial efficacy screening

Efficacy assessment of probiotics, prebiotics, nutraceuticals and other food supplements

Substrate for probiotic delivery and temporary in situ hosting

Preserve subjects microbiota during sample transport

Substrate to manufacture bacteria-derived products with higher yield

ABOUT US

Daniela Pacheco

Daniela Pacheco

Materials Engineering
Pharmaceutical Technology
PhD from Politecnico di Milano

Sebastião van Uden

Sebastião van Uden

Bioengineering
Biomedical Engineering
PhD from Politecnico di Milano

Paola Petrini

Paola Petrini

Biomaterial Science
In vitro models
Professor at Politecnico di Milano

Livia Visai

Livia Visai

Microbiology
Nanomedicine
Professor at University of Pavia

Sonja Visentin

Sonja Visentin

Pharmaceutical Sciences
Biotechnology
Professor at University of Turin

ACHIEVEMENTS

Winner 2018

Innovation in
Bioengineering Award

Winner 2018

Switch2Product Award
PoliHub-Deloitte

Finalist 2019

StartCup
Lombardia

2 Young Scientist Awards 2019

Italian Inter-University Center
for the Promotion of the 3Rs
Principles in Teaching &
Research (Centro 3R)

Young Scientist Travel Award 2019

22nd European Congress on
Alternatives to Animal Testing

IN THE MEDIA

CONTACT US

Would you like to know more about Bac3Gel?

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contact@bac3gel.com