Bac3Gel
Modelling human mucus
TECHNOLOGY
Bac3Gel technology aims to model a range of different human mucus in physiological and pathological conditions.
Due to the distinctive features of Bac3Gel, it is also possible to recreate human microbiota in vitro to be used by Pharma, Cosmetic and Food Industries, Contract Research Organisations (CRO) and Research laboratories.
Bac3Gel is an upcoming startup from Politecnico di Milano.
Mucus Models
Models of physiologic or pathologic mucus of different body districts: lung, intestinal, stomach or vaginal.
Gradient Structure
Bac3Gel can be made with a gradient of oxygen, nutrients and bacterial motility.
Compatibility
Compatible with multiwell plates, bioreactors, Transwell(R), PAMPA systems and cell monolayers.
Microbiota in vitro
Simultaneously hosts different and competitive microorganisms.
Fully tuneable
The chemistry, gradient, viscoelastic properties, structure and thickness of Bac3Gel are fully tuneable.
Mucus barrier
Reproduces the interactive and steric barriers of human mucus, for appropriate drug screening.
POTENTIAL APPLICATIONS
Compound permeability through the human mucus barrier
Universal 3D substrate for bacterial culture
Antimicrobial efficacy screening
Efficacy assessment of probiotics, prebiotics, nutraceuticals and other food supplements
Substrate for probiotic delivery and temporary in situ hosting
Preserve subjects microbiota during sample transport
Substrate to manufacture bacteria-derived products with higher yield
ABOUT US
Daniela Pacheco
Materials Engineering
Pharmaceutical Technology
PhD from Politecnico di Milano
Sebastião van Uden
Bioengineering
Biomedical Engineering
PhD from Politecnico di Milano
Paola Petrini
Biomaterial Science
In vitro models
Professor at Politecnico di Milano
Livia Visai
Microbiology
Nanomedicine
Professor at University of Pavia
Sonja Visentin
Pharmaceutical Sciences
Biotechnology
Professor at University of Turin
ACHIEVEMENTS
Winner 2018
Innovation in
Bioengineering Award
Winner 2018
Switch2Product Award
PoliHub-Deloitte
Finalist 2019
Lombardia
2 Young Scientist Awards 2019
Italian Inter-University Center
for the Promotion of the 3Rs
Principles in Teaching &
Research (Centro 3R)
Young Scientist Travel Award 2019
Alternatives to Animal Testing
IN THE MEDIA
CONTACT US
Would you like to know more about Bac3Gel?
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contact@bac3gel.com