Universal substrate for 3D bacterial culture

Screening with higher precision

MISSION

Bac3Gel technology enables to mimic a range of different human mucus in physiological and pathological conditions.

Due to the distinctive features of Bac3Gel, it is now possible to recreate human microbiota in vitro to be used by Pharma and Cosmetic Industries, Contract Research Organisations (CRO) and Research laboratories.

TECHNOLOGY

Gradient Structure

Typical of physiologic intestinal, stomach and vaginal mucus, and pathologic lung mucus

Fully tunable

All parameters can be modified: chemistry, gradient, viscoelastic properties, structure and thickness

Recreate Microbiota in vitro

Host different microorganisms simultaneously typical of intestinal, lung and vaginal microbiota

Mucus barrier

Reproduces the interactive and steric barriers of mucus

APPLICATIONS

In vitro screening technology for drug discovery and development to determine:
– Mucus Permeability
– Antimicrobial Susceptibility
– The efficacy of probiotics, prebiotics, nutraceuticals and other food supplements

Preserve subjects/patients microbiota during sample transport
Substrate to manufacture bacteria-derived products with higher yield

TEAM

Daniela Pacheco, CTO

Daniela Pacheco, CTO

Materials Engineering
Pharmaceutical Technology

Sebastião van Uden, CEO

Sebastião van Uden, CEO

Bioengineering
Biomedical Engineering

Professor Paola Petrini

Professor Paola Petrini

Biomaterial Science
Member of Italian 3Rs Centre

Professor Livia Visai

Professor Livia Visai

Microbiology
Nanomedicine

Professor Sonja Visentin

Professor Sonja Visentin

Pharmaceutical Sciences
Biotechnology

ACHIEVEMENTS

Winner 2018

Innovation in
Bioengineering Award

Winner 2018

Switch2Product Award
PoliHub-Deloitte

Finalist 2019

StartCup
Lombardia

2 Young Scientist Awards 2019

Italian Inter-University Center
for the Promotion of the 3Rs
Principles in Teaching &
Research (Centro 3R)

Young Scientist Travel Award 2019

22nd European Congress on
Alternatives to Animal Testing

IN THE MEDIA

CONTACT US

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